Kangfulong Can Promote Protein Assimilation Hormone Drugs

The synthetic methods

The product can be prepared by acetylation, reduction, ring opening, oxidation, hydrolysis, elimination, oxime, rearrangement, hydrolysis, addition, oxidation, hydrolysis, condensation and other multi-step reactions of saponin or sisal.

use

The intermediate of Corylon. It can promote protein synthesis and inhibit protein heterogenesis, reduce blood cholesterol, reduce calcium and phosphorus excretion, alleviate bone marrow inhibition, promote development, and promote tissue regeneration and granulation formation. It has preventive and antagonistic effect on adrenocortical dysfunction caused by long-term use of adrenocortical hormone. [2]

Compound related drug description broadcast

Pharmacological effects

Hydroxymethylenone can promote protein synthesis and inhibit protein allogenesis, reduce blood cholesterol, reduce calcium and phosphorus excretion, alleviate bone marrow inhibition, promote development, promote tissue regeneration and granulation formation. Its protein assimilation was 4 times that of methyl testosterone, its androgen activity was 0.39 times that of methyl testosterone, and its differentiation index was about 10.5. It has antagonistic effect on protein dissimilation caused by excessive adrenal corticosteroid, and has preventive and antagonistic effect on adrenal cortical dysfunction caused by long-term use of adrenal corticosteroid.

indications

It is used in osteoporosis, chronic wasting disease, old age and infirm, serious disease, weak and emaciated after operation, childhood hypoplasia, aplastic anemia, leukopenia, hyperlipidemia, etc.

contraindicated

Patients with liver and kidney insufficiency, prostate cancer and pregnant women are forbidden.

Usage.

Orally, 5 ~ 10mg per day, divided into 1 ~ 3 times. Dosage for children: 1.25 to 5mg per day. For osteoporosis, 2.5mg each time, 3 times a day, or up to 20mg a day. For aplastic anemia, 1 ~ 5mg/kg daily.

Adverse reactions

Occasionally see nausea, oedema, liver dysfunction and icteric. Young women occasionally delayed menstruation phenomenon, withdrawal can be restored.

Matters needing attention

1. Do not take the medicine for more than 30 days for children and less than 90 days for adults.

2. For aplastic anemia, medication time may be longer. [3]

Expert Comment broadcast

The assimilation of hydroxymethylenolone protein was 4 times that of MEt, the androgen activity was 0.39 times that of MET, and the differentiation index was about 10.5.