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Sibutramine Original Packing In Blue Barrel Purity 99.8 CAS 106650-56-0

Sibutramine Original Packing In Blue Barrel Purity 99.8 CAS 106650-56-0

Sibutramine Original Packing In Blue Barrel Purity 99.8 CAS 106650-56-0
Sibutramine Original Packing In Blue Barrel Purity 99.8 CAS 106650-56-0
Sibutramine Original Packing In Blue Barrel Purity 99.8 CAS 106650-56-0
Product Details:
Place of Origin: India
Brand Name: LiHui
Certification: Hplc ISO9001
Model Number: 106650-56-0
Payment & Shipping Terms:
Minimum Order Quantity: 100g
Price: Negotiated
Packaging Details: Foil Bag
Delivery Time: 3-7days after received payment
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000Kg Per Month
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Detailed Product Description
CAS: 106650-56-0 Color Or Appearance: White Crystalline Powder
Packing Specification: Aluminum Foil Bag Or Aluminum Tin 25 Kg/barrel Execution Standard: USP42
Product Purity: 99% The Product Level: Pharmaceutical Grade
Molecular Formula: C17H26ClN
High Light:

Purity 99.8 Sibutramine

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CAS 106650-56-0 Sibutramine

The basic information

Chinese name: Sibutramine

Chinese alias: N-(1-(1-(4-chlorophenyl) cyclobutyl)-3- methyl butyl)-N,N- dimethylamine

Sibutramine

CAS no. : 106650-56-0

Molecular formula: C17H26ClN

Molecular weight: 279.85

Accurate quality: 279.17500

PSA: 3.24000

LogP: 4.73800

Physical and chemical properties

Properties: white crystalline powder

Melting point: 191-192 ° C

Molecular structure data

1. Molar refractive index: 83.76

2. Molar volume (CM3 /mol) : 271.3

3, equal tension specific volume (90.2K) : 670.5

4. Surface tension (DYNE /cm) : 373.3

5, polarization (10-24cm3) : 33.2

6, single isotope mass: 279.175378 Da

7, nominal quality: 279 Da

8, average quality: 279.848DA

Computational chemical data

1. Reference value of hydrophobic parameter Calculation (XlogP) : 5.4

2. Number of hydrogen bond donors: 0

3. Number of hydrogen bond receptors: 1

4. Number of rotatable bonds: 5

5. Tautomeric number: 0

6. Polar surface area of topological molecules: 3.2

Number of heavy atoms: 19

8. Surface charge: 0

9. Complexity: 275

10. Isotope atomic number: 0

11. Determine the number of primary structural centers: 0

12. Number of uncertain atomic construction centers: 1

13. Determine the number of chemical bond centers: 0

14. Number of uncertain chemical bond centers: 0

15. Number of covalent bond units: 1 [1]

Sibutramine Original Packing In Blue Barrel Purity 99.8 CAS 106650-56-0 0Sibutramine Original Packing In Blue Barrel Purity 99.8 CAS 106650-56-0 1

 

Gefitinib Description

Gefitinib (ZD1839) (INN, , trade name Iressa, marketed by AstraZeneca and Teva), is a drug used for certain breast, lung and other cancers. Gefitinib is an EGFR inhibitor, like erlotinib, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR. However, meta-analyses have not shown any improvement in overall survival, that is, it does not extend life.

Gefitinib is used to treat non-small cell lung cancer that has spread to other parts of the body in people with certain types of tumors. Gefitinib is in a class of medications called kinase inhibitors. It works by blocking the action of a certain naturally occurring substance that may be needed to help cancer cells multiply.

How to use Gefitinib

Gefitinib comes as a tablet to take by mouth. It is usually taken with or without food once a day. Take gefitinib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take gefitinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you are unable to swallow the tablets, you may dissolve them in water. Place one tablet in 4 to 8 ounces (120 to 240 mL) of plain, noncarbonated drinking water. Stir with a spoon for about 15 minutes until the tablet is dissolved. Drink the mixture right away. Rinse the glass with another 4 to 8 ounces (120 to 240 mL) of water and drink the rinse water right away to be sure that you swallow all of the medication.

Your doctor may delay or permanently stop your treatment if you experience certain side effects. Be sure to tell your doctor how you are feeling during your treatment with gefitinib.

Gefitinib Specification


Tests

Specification

Results

Appearance

Slight white to white crystalline powder

White crystalline powder

Identification IR(1)

Conforms to the refence

Conforms to the refence

Melting Point

194.0~198.0°C

196.0~197.0°C

Water(KF)

≤0.30%

0.05%

Assay (HPLC)

≥99.0%

99.9%

Individual Purity (HPLC )

≤0.20%

0.09%

Conclusion

Conform with company standard

 

 

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