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Contraception Female Anabolic Steroids Raw Powder Drospirenone CAS 67392-87-4

Product Name: Drospirenone
Synonyms: ,5'(2h)-dione,1,3',4',6,7,8,9,10,11,12,13,14,15,16,20,21-hexadecahydro-10,13-;1,2-dihydrospirorenone;15-beta,16-beta-dimethylene-3-oxo-17-alpha-pregn-4-ene-21,17-c;17-beta))-16-alpha;6-beta,7-beta;arbolactone;dimethyl-,(6r-(6-alpha,7-alpha,8-beta,9-alpha,10-beta,13-beta,14-alpha,15-alph;spiro(17h-dicyclopropa(6,7:15,16)cyclopenta(a)phenanthrene-17,2'(5'h)-furan)-3
: 67392-87-4
MF: C24H30O3
MW: 366.49
EINECS: 266-679-2

Chemical Properties Off-White Crystalline Powder
Usage Synthetic progestogen exhibiting antimineralocorticoid and antiandrogenic activity.
Usage antiviral
Usage anti-cancer therapeutic

Descriptions:

Drospirenone (INN, USAN), also known as 1,2-dihydrospirorenone, is a synthetic hormone used in birth control pills and postmenopausal hormone replacement therapy pills.It is sold under the brand names Yasmin, Yasminelle, Yaz, Beyaz, Ocella, Zarah, Daylette and Angeliq, all of which arecombination products of drospirenone with an estrogen such as ethinylestradiol or estradiol. Drospirenone differs from other synthetic progestins in that its pharmacological profile in preclinical studies shows it to be closer to the natural progesterone. As such it has potent antimineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and has also been shown to possess mild antiandrogen activity.The antimineralocorticoid properties exhibited by drospirenone promote sodium excretion and prevent water retention.

It is a new synthetic progestin with anti mineralocorticoid activity. Its pharmacological properties are similar to that of endogenous progesterone. It can form an effective, safe and short acting contraceptive pill with estradiol and estradiol. Drospirenone is an ingredient in some birth control pills and hormone replacement therapy. In combination with ethinyl estradiolit is used as contraception, and for women who want contraception it is also approved by the U. S. Food and Drug Administration(FDA) to treat moderate acne and premenstrual dysphoric disorder.

Drospirenone is the only progesterone that has the characteristics similar to the natural progesterone currently, its structure is more like that of the natural progesterone compare with the structure of the progesterone contained in the traditional oral contraceptives.Except the effect of anti-androgen, drospirenone has the role of anti-mineralocorticoid which can prevent water and sodium retain in the body. Not only it has the a great effectivenes of contraception, there are also many good impacts on women's health like reducing the acne, making the skin more smooth and controling the weight efficaciously.

Drospirenone is an aldosterone antagonist with potassium-sparing properties, though in most cases no increase of potassium levels is to be expected. In women with mild or moderate renal insufficiency, or in combination with chronic daily use of other potassium-sparing medications (ACE inhibitors, angiotensin II receptor antagonists, potassium-sparing diuretics, heparin, aldosterone antagonists, or NSAIDs), a potassium level should be checked after two weeks of use to test for hyperkalemia.

Applications:

Flexor screw ketone (Drospirenone) is a kind of resistance mineralocorticoid activity of new synthetic progesterone, its pharmacological properties similar to endogenous progestin, with ethinylestradiol constitute a kind of high efficiency, good safety and high degree of acceptance of a short-acting contraceptives.

Drospirenone is an ingredient in some birth control pills and hormone replacement therapy. In combination with ethinyl estradiolit is used as contraception, and for women who want contraception it is also approved by the U. S. Food and Drug Administration(FDA) to treat moderate acne and premenstrual dysphoric disorder. Drospirenone and ethinyl estradiol combination is used to prevent pregnancy. It is a birth control pill that contains two types of hormones, ethinyl estradiol and drospirenone, and when taken properly, prevents pregnancy. It works by stopping a woman's egg from fully developing each month. The egg can no longer accept a sperm and fertilization is prevented.

Drospirenone and ethinyl estradiol combination is used to prevent pregnancy. It is a birth control pill that contains two types of hormones, ethinyl estradiol and drospirenone, and when taken properly, prevents pregnancy. It works by stopping a woman's egg from fully developing each month. The egg can no longer accept a sperm and fertilization is prevented.

Drospirenone is 8–10 times more potent as an antimineralocorticoid relative to spironolactone (3 mg drospirenone is equivalent to about 20–25 mg spironolactone in this regard. It is more potent as an antiandrogen relative to spironolactone also but is less potent relative to cyproterone acetate, having about one-third the potency of this drug. Progestogenic, antimineralocorticoid, and mild antiandrogenic effects have been observed in humans during treatment with drospirenone at a dosage range of 0.5 to 4 mg per day orally. The antimineralocorticoid properties exhibited by drospirenone promote sodium excretion and prevent water retention.

Drospirenone (INN, USAN), also known as 1,2-dihydrospirorenone, is a synthetic hormone used in birth control pills and postmenopausal hormone replacement therapy pills. all of which are combination products of drospirenone with an estrogen such as ethinylestradiol or estradiol.