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Gefitinib Pharmaceutical Raw Material Powder Cas 184475-35-2 Anti Tumor

Gefitinib Pharmaceutical Raw Material Powder Cas 184475-35-2 Anti Tumor

  • Gefitinib Pharmaceutical Raw Material Powder Cas 184475-35-2 Anti Tumor
  • Gefitinib Pharmaceutical Raw Material Powder Cas 184475-35-2 Anti Tumor
Gefitinib Pharmaceutical Raw Material Powder Cas 184475-35-2 Anti Tumor
Product Details:
Place of Origin: China
Brand Name: LiHui
Certification: Hplc ISO9001
Model Number: 184475-35-2
Payment & Shipping Terms:
Minimum Order Quantity: 100g
Price: Negotiated
Packaging Details: Foil Bag
Delivery Time: 3-7days after received payment
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000Kg Per Month
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Detailed Product Description
CAS: 184475-35-2 Color Or Appearance: White Crystalline Powder
Packing Specification: Aluminum Foil Bag Or Aluminum Tin 25 Kg/barrel Execution Standard: USP42
Product Purity: 99% The Product Level: Pharmaceutical Grade
Molecular Formula: C22H24ClFN4O3
High Light:

Gefitinib Pharmaceutical Raw Material Powder

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Pharmaceutical Raw Material Powder 184475-35-2

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Gefitinib Anti Tumor

High Effective Anti-tumor Pharmaceutical Raw Material Powder Gefitinib Cas 184475-35-2

 

 

Product Name: Gefitinib
Synonyms: Gefitinib N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;IRESSA;GEFITINIB;AKOS 91371;n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine;Gefitinib 184475-35-2;Gefitinib(TINIBS)
CAS: 184475-35-2
MF: C22H24ClFN4O3
MW: 446.9
EINECS: 643-034-7
Chemical Properties Light-Yellow Crystalline Powder
Uses Gefitinib (Iressa, ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively.
Uses Gefitinib is an antineoplastic.
Anti Tumor Pharmaceutical 99% Gefitinib Cas 184475-35-2 0

Gefitinib Description

Gefitinib (ZD1839) (INN, , trade name Iressa, marketed by AstraZeneca and Teva), is a drug used for certain breast, lung and other cancers. Gefitinib is an EGFR inhibitor, like erlotinib, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR. However, meta-analyses have not shown any improvement in overall survival, that is, it does not extend life.

Gefitinib is used to treat non-small cell lung cancer that has spread to other parts of the body in people with certain types of tumors. Gefitinib is in a class of medications called kinase inhibitors. It works by blocking the action of a certain naturally occurring substance that may be needed to help cancer cells multiply.

How to use Gefitinib

Gefitinib comes as a tablet to take by mouth. It is usually taken with or without food once a day. Take gefitinib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take gefitinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you are unable to swallow the tablets, you may dissolve them in water. Place one tablet in 4 to 8 ounces (120 to 240 mL) of plain, noncarbonated drinking water. Stir with a spoon for about 15 minutes until the tablet is dissolved. Drink the mixture right away. Rinse the glass with another 4 to 8 ounces (120 to 240 mL) of water and drink the rinse water right away to be sure that you swallow all of the medication.

Your doctor may delay or permanently stop your treatment if you experience certain side effects. Be sure to tell your doctor how you are feeling during your treatment with gefitinib.

Gefitinib Specification


Tests

Specification

Results

Appearance

Slight white to white crystalline powder

White crystalline powder

Identification IR(1)

Conforms to the refence

Conforms to the refence

Melting Point

194.0~198.0°C

196.0~197.0°C

Water(KF)

≤0.30%

0.05%

Assay (HPLC)

≥99.0%

99.9%

Individual Purity (HPLC )

≤0.20%

0.09%

Conclusion

Conform with company standard

 

Anti Tumor Pharmaceutical 99% Gefitinib Cas 184475-35-2 1

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