C20H24O2 Natural Anti Estrogen Supplements Exemestane Aromasin CAS 107868-30-4

Anti Estrogen Pharmaceutical Raw Materials Exemestane Aromasin CAS 107868-30-4

Detail:

Product Name: Exemestane (Aromasin)

CAS NO: 107868-30-4

MF: C20H24O2

MW: 296.4

Melting point : 155.13°C

storage temp.: Store at -20°

Ccolor : white to off-white

Chemical Properties: white to light yellow crystal powder

Uses: An antineoplastic (hormonal)Uses antiinfectiveUses Labeled Exemestane, intended for use as an internal standard for the quantification of Exemestane by GC- or LC-mass spectrometry.

Discreption:

Exemestane is a steroidal Aromatase Inhibitor (AI) that is most commonly known as Aromasin
Exemestane is officially classified as a steroidal suicide Aromatase Inhibitor, and carries the ability to
inhibit the aromatase enzyme, which is responsible for the production or conversion of testosterone to
estrogen. Exemestane has the ability to block aromatization, which in turn inhibits the production of
estrogen, and thereby lowers the body’s serum estrogen levels. This will prove useful to breast cancer
patients as breast cancer often feeds off the estrogen hormone. It will also prove useful to the anabolic
steroid user.Because it protects against estrogenic related side effects.
Many anabolic steroids have the ability to increase estrogen levels due to the aromatase process,
specifically the conversion of testosterone to estrogen. This can lead to gynecomastia and water
retention. Excess water retention can also promote high blood pressure when it becomes severe. Steroids that do not carry a strong estrogenic nature can also cause these effects, most notably gynecomastia if they carry a progestin nature.

Applications:

Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.
The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by the aromatase enzyme in the peripheral tissues (i.e. adipose tissue like that of the breast) and a number of sites in the brain. Estrogen is produced locally via the actions of the aromatase enzyme in these peripheral tissues where it acts locally. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system.
Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition." By being structurally similar to enzyme targets, Exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen.
Exemestane is taken in tablet form once a day. Patients can experience side effects like nausea, anxiety, shortness of breath, abdominal pain, bone pain, and chest pain. Side effects vary widely between patients and patients should report the side effects they experience to their doctors, as some may be indicators of dangerous complications. Shortness of breath and chest pain in particular are causes for concern in patients taking exemestane.

COA:

Use:

Exemestane has the ability to stimulate natural testosterone production, which is precisely why some will
include it during their PCT. Like Arimidex and Letrozole, Aromasin will stimulate the pituitary to release
more Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH), two hormones essential to natural testosterone production. While the other common AI’s share this trait, Exemestane has been shown to carry a slight androgenic effect, as well as the ability to increase the production of Insulin-Like Growth Factor-1 (IGF-1). This is a trait no other AI can claim to carry. By using Exemestane during PCT, the individual receives the desired testosterone boost necessary for recovery, but with the IGF-1 increase
also creates a stronger anabolic atmosphere. This is deemed useful by some steroid users as it could
potentially give them the ability to protect their lean tissue all the more during use. However, when we look at the direct effects of Exemestane as it pertains to PCT, we will find PCT use is normally not
recommended despite these positive effects.

Aromasin (Exemestane) cycle or dose reviews:

In a performance setting, standard Aromasin doses will normally be 12.5-25mg every other day. Most should be fine with 12.5mg every other day, with some getting by with only two to three doses per week. The individual’s total sensitivity and the composition of the steroid in cycle in question will dictate the final outcome. There will be, however, some who require a daily dose with as much as 25mg per day. This should be short lived and only continued as long as necessary due to the possible cholesterol issues. This type of use can prove very useful for the competitive bodybuilder 7-14 days leading up to the completion in an effort to come in as dry and hard as possible. But again, this full dose use is only used for a limited time.

Aromasin (Exemestane) Analysis:

1. Save Money: The cost is only 40-60% of the normal cost.
2. Save Time:They take only a short time to prepare.
3. Convenient Ship:They are easier and cheaper to ship than amps or vials.
4. Safer Delivery: Less chance of your order getting seized by customs.
5. Better compensate :Unlike vials and Ampullas, they come with some refund / reship policy.

Packaging & Delivery:

We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.

Our advantages:

1. Shanghai Taigui Pharmaceutical Technology Co., Ltd is a professional raw powder factory in China for
over 10 years, all powders are factory directly supplying.

2. Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA,
Australia, Japan, Korea and many other countries, over 3000t each month.

3. Professional team special for package and shipment and staring on tracking code 24hours for customs
pass guaranteed. 100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil; 98% pass to
Germany,Russia, Australia, New Zealand.

4. Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24hours.

5. High quality, good price, fast and safety delivery. Shipment by DHL, TNT, FEDEX, HKEMS, UPS, etc.