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Cas 144060-53-7 Allopurinol Febuxostat For Gout Treatment

Cas 144060-53-7 Allopurinol Febuxostat For Gout Treatment

  • Cas 144060-53-7 Allopurinol Febuxostat For Gout Treatment
  • Cas 144060-53-7 Allopurinol Febuxostat For Gout Treatment
Cas 144060-53-7 Allopurinol Febuxostat For Gout Treatment
Product Details:
Place of Origin: China
Brand Name: LiHui
Certification: Hplc ISO9001
Model Number: 144060-53-7
Payment & Shipping Terms:
Minimum Order Quantity: 100g
Price: Negotiated
Packaging Details: Foil Bag
Delivery Time: 3-7days after received payment
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000Kg Per Month
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Detailed Product Description
CAS: 144060-53-7 Color Or Appearance: White Crystalline Powder
Packing Specification: Aluminum Foil Bag Or Aluminum Tin 25 Kg/barrel Execution Standard: USP42
Product Purity: 99% The Product Level: Pharmaceutical Grade
Molecular Formula: C16H16N2O3S
High Light:

Cas 144060-53-7

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144060-53-7 Allopurinol Febuxostat

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Allopurinol Febuxostat For Gout Treatment

High Quality Febuxostat API Powder Cas No 144060-53-7 For Gout Treatment

 

 

Description

Febuxostat is a new generation of xanthine oxidase inhibitor developed by Japanese company. It is used in the treatment of gout. Its structure is totally different from that of xanthine oxidase inhibitor developed 40 years ago. It is a new and efficient selective inhibitor of non purine xanthine oxidase. Xanthine oxidase is the key enzyme to promote the production of uric acid. Febuxostat can reduce the level of chemical Book uric acid in the blood of gout patients with hyperuricemia. The clinical research shows that the product is safe and effective. The product is metabolized through the liver and does not depend on renal excretion. Therefore, it is not necessary to reduce the dosage of febuxostat in patients with moderate to severe hepatorenal insufficiency. The dosage is 40 mg or 80 mg once a day. It is not recommended to treat gout patients without hyperuricemia. In February 2009, the U.S. Food and Drug Administration (FDA) approved febuxostat for the long-term treatment of gout hyperuricemia.

 

Product Parameters

 

CAS No. 144060-53-7
Molecular Formula C16H16N2O3S
LogP 3.72318
PSA 111.450
Flash point 278.3°C
Melting point 238-239°(dec.)
Boiling point 536.6±60.0 °C(Predicted)
Density 1.31g/cm3
Shelf life 2 Years

 

Function

 

Gout is a group of heterogeneous diseases, which is caused by heredity or acquisitiveness. Due to the excessive production of uric acid in the body and the decrease of renal clearance, the accumulation of uric acid in the body leads to the deposition of urate crystals in joints and organs. Therefore, gout is usually treated by promoting the excretion of uric acid and inhibiting the production of uric acid, and taking appropriate measures to improve the related symptoms.
The production of uric acid in vivo is related to purine metabolism. In the last step of purine metabolism, hypoxanthine generates xanthine under the action of xanthine oxidoreductase (XOR), and then further generates uric acid. Inhibiting the activity of XOR can effectively reduce the production of uric acid. Febuxostat is a new generation of non purine selective xanthine oxidase inhibitor. It can reduce the synthesis of uric acid in vivo and the concentration of uric acid through highly selective action on the oxidase, so as to effectively treat ventilation diseases.

Gout Treatment Cas No 144060-53-7 Febuxostat API Powder 0

Fuction and Application of Febuxostat

(1) the allopurinol only have inhibition to reduced the XOR, rather than cloth sutent XOR of
oxidation and reduced significantly inhibitory effect, more powerful, durable and its effect in
lowering uric acid;
(2) because allopurinol is a purine analogues, it is inevitable to affect the metabolism of other
enzymes involved in purine and pyridine metabolism.So in allopurinol treatment, you need to
repeat a large dose to maintain a high level of medication.It also leads to serious and even fatal
adverse reactions caused by drug accumulation.Instead of being a non-purine XOR inhibitor, it
has better security.

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Gout Treatment Cas No 144060-53-7 Febuxostat API Powder 1

Packaging & Logistics

Package:

1kg per Foil Bag, 10 Bags per carton. 25 kg per Drum. Or Customized Package.

2. Shipping Advise:

1. By Express

------Suitable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to pick up the goods.

2. By Air

------Suitable for more than 50 kg, Fast:4-5 days, High cost, airport to airport. professional broker needed.

3. By sea

------Suitable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, professional broker needed.

Contact Details
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Tel: +8613777515435

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