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CAS: | 125-69-9 | Color Or Appearance: | White Crystalline Powder |
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Product Use: | To Treat Obesity. | Packing Specification: | Aluminum Foil Bag Or Aluminum Tin 25 Kg/barrel |
Execution Standard: | USP42 | Product Purity: | 99% |
The Product Level: | Pharmaceutical Grade | Molecular Formula: | C18H26BrNO |
High Light: | 125-69-9 Fat Loss Steroids,125-69-9 DXM Powder,Fat Loss Steroids DXM |
CAS 125 69 9 Fat Loss Steroids DXM Powder Dextromethorphan Hydrobromide / Romilar
Product Name: Dextromethorphan Hydrobromide
Synonyms:Delsym;Sisaal;Dextro;ROMILAR;medicon;tusilan;Tussade;antussan;metrorat;Dormetan;;Romilar;Tussade;
CAS No.: 125-69-9
Einecs No:204-750-1
Molecular Formula: C18H26BrNO
Molecular Weight: 352.31
Purity: 99.0%
Appearance: white crystalline powder
Standard: Enterprise Standard
Packing: 25KG/Drum or as per your requirements
Application: medical use
Dextromethorphan Hydrobromide (DXM or DM) is a drug of the morphinan class with sedative,
dissociative, and stimulant properties (at higher doses). It is a cough suppressant in many over-the-
counter cold and cough medicines including generic labels and store brands, Dextromethorphan
Hydrobromide has also found numerous other uses in medicine, ranging from pain relief (as either the
primary analgesic, or an opioid potentiator) over psychological applications to the treatment of addiction. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, Dextromethorphan Hydrobromide
occurs as a white powder.
DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan
acts as a dissociative anesthetic. Its mechanism of action is via multiple effects, including actions as a
nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist.DXM and its major metabolite,
dextrorphan, also act as an NMDA receptor antagonist at high doses, which produces effects similar to,
yet distinct from, the dissociative states created by other dissociative anesthetics such as ketamine and
phencyclidine. Further, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level
metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below
that of DXM.
Abstract
Dextromethorphan Hydrobromide is the hydrobromide salt form of dextromethorphan, a synthetic, addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.
Dextromethorphan Hydrobromide (DXM or DM) is an antitussive (cough suppressant) drug of the morphinan class with sedative and dissociative properties. It is one of the active ingredients in many over-the-counter cold and cough medicines, including generic labels and store brands, Benylin DM, Mucinex DM, Robitussin, NyQuil, Dimetapp, Vicks, Coricidin, Delsym, TheraFlu, and others. Dextromethorphan has also found numerous other uses in medicine, ranging from pain relief (as either the primary analgesic, or an opioid potentiater) over psychological applications to the treatment of addiction. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.
Product Name | Dextromethorphan Hydrobromide |
Synonyms | Dextromethorphan maleate HBR; dextromethorphan HBR; (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan hydrobromide; 3-methoxy-17-methylmorphinan hydrobromide; (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan hydrobromide hydrate; Destromethorphan hydrobromide |
Molecular Formula | C18H28BrNO2 |
Molecular Weight | 370.3244 |
InChI | InChI=1/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15-,17+,18+;;/m1../s1 |
CAS Registry Number | 125-69-9 |
EINECS | 204-750-1 |
Molecular Structure | |
Boiling point | 486.1°C at 760 mmHg |
Flash point | 247.8°C |
Vapour Pressure | 2.92E-10mmHg at 25°C |
Assay | 99% |
Appearance | White or white crystalline powder |
Application
DXM is also used recreationally.When exceeding label-specified maximum dosages,dextromethorphan acts as a dissociative hallucinogen.Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist.
The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonist.In high doses this produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetic such as and .As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.
Use
1.For dry cough,including upper respiratory tract infection (such as cold,pharyngitis,bronchitis,cough).
2.Research reagents,widely used in molecular biology,pharmacology research.This is the central antitussive,can inhibit the medulla cough centrum antitussive effect and produce.The antitussive effect is equal to or slightly.The general treatment dose not inhibit respiration,long-term use of no addiction and tolerance.
Competitive Advantage:
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