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Theophylline Anhydrous Oral Hypoglycemic Agents Raw Materials For Pharma Industry

Theophylline Anhydrous Oral Hypoglycemic Agents Raw Materials For Pharma Industry

Theophylline Anhydrous Oral Hypoglycemic Agents Raw Materials For Pharma Industry
Theophylline Anhydrous Oral Hypoglycemic Agents Raw Materials For Pharma Industry
Theophylline Anhydrous Oral Hypoglycemic Agents Raw Materials For Pharma Industry
Product Details:
Place of Origin: China
Brand Name: LiHui
Certification: Hplc ISO9001
Model Number: 58-55-9
Payment & Shipping Terms:
Minimum Order Quantity: 100g
Price: Negotiated
Packaging Details: Foil Bag
Delivery Time: 3-7days after received payment
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000Kg Per Month
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Detailed Product Description
CAS: 58-55-9 Color Or Appearance: White Crystalline Powder
Product Use: Lower Blood Sugar Packing Specification: Aluminum Foil Bag Or Aluminum Tin 25 Kg/barrel
Execution Standard: USP42 Product Purity: 99%
The Product Level: Pharmaceutical Grade Molecular Formula: C26H28Cl2N4O4
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Theophylline Anhydrous Oral Hypoglycemic Agents

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58-55-9 Oral Hypoglycemic Agents

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58-55-9 Raw Materials For Pharma Industry

CAS 58-55-9 Pharmaceutical Raw Materials Theophylline For Bronchial Cardiogenic Asthma
 
Basic Info
Synonyms: Theophylline anhydrous; 1,3-dimethyl-3,4,5,7-tetrahydro-1H-purine-2,6-dione; dimethylxanthine; ANHYDROUS THEOPHYLLINE
CAS: 58-55-9
EINECS: 200-385-7
Density: 1.62g/cm3
Melting Point: 270-274℃
Boiling Point: 390.1°C at 760 mmHg
Flash Point: 189.7°C
Solubility:H2O: 8.3 g/L (20℃)
Appearance: white crystals
Package: 25KG/DRUM
Storage: ventilating and drying
Usage:
Pharmaceutical intermediates;
Relaxing bronchial smooth muscle;
Increasing heart muscle contractility and efficiency; as a positive inotrope;
Increasing heart rate: (positive chronotropic);
Increasing blood pressure;
Increasing renal blood flow;
Anti-inflammatory effects;
Central nervous system stimulatory effect mainly on the medullary respiratory center.
CAS 58 55 9 Pharmaceutical Raw Materials Theophylline For Bronchial Cardiogenic Asthma 0
Description
 
It can reduce the tension of smooth muscle, dilate the airway; promote the release of endogenous adrenaline and norepinephrine, relax the airway smooth muscle; inhibit the release of calcium ions from the smooth muscle endoplasmic reticulum, reduce the intracellular calcium concentration and produce airway dilation . Theophylline has a stronger relaxing effect on smooth muscle but less than a beta agonist.
 
Application
 
1. For bronchial asthma, acute bronchitis, asthmatic bronchitis, obstructive emphysema, etc., to relieve wheezing symptoms. Also suitable for symptoms of bronchospasm associated with chronic bronchitis and emphysema.
2. Can be used for patients with cardiogenic asthma, cardiogenic edema and acute cardiac insufficiency.
3. Can also be used for patients with biliary colic.
 
Precautions
 
This product should be taken after meals to reduce gastrointestinal irritation; smoking, chronic alcoholism and induction of liver drug enzymes can reduce the plasma concentration of theophylline, theophylline dose needs to be appropriately increased. Theophylline can cause arrhythmia, worsening the original arrhythmia, and any changes in the patient's heart rate or heart rate should be closely watched.
 
When the theophylline is injected intravenously or the plasma concentration of theophylline is higher than 20 μg/ml, toxicity may occur, which may be arrhythmia, increased heart rate, muscle fibrillation, epilepsy, transient hypotension or peripheral circulatory failure. When the concentration of theophylline is higher than 40μg/ml, fever, water loss, convulsions, etc. may occur, and severe cases may cause death due to respiratory and cardiac arrest, and pre-treatment of sedatives can be effectively prevented.
Cetificate of Analysis
 

Product nameTheophylline
CAS No.58-55-9Outer Packing25KGS
Production date2018.03.03Shelf life2022.03.02
Standard adoptedBP2015
Items of analysisSpecificationResults
AppearanceWhite Crystalline PowderConforms
IdentificationPositive reactionConforms
Acidity50ml solution S consumption 0.02mol / NaOH ≤ 1mlConforms
Appearance of the solutionClarified colorlessConforms
Relative substanceImpurities ABCD are less than 01%; other impurities are less than 0.1%; total impurities are less than 0.5%Conforms
Heavy metal≤20ppm<20ppm
Loss on drying≤0.5%0.13%
Sulfated ash≤0.1%0.04%
Melting point270-274℃271.3-272.0℃
Assay99-101.0%99.5%
ConclusionQualified

 
CAS 58 55 9 Pharmaceutical Raw Materials Theophylline For Bronchial Cardiogenic Asthma 1
Product Application
Theophylline is a smooth muscle relaxant used chiefly for its bronchodilator effect, treating of chronic obstructive pulmonary emphysema(COPD), bronchial asthma, chronic bronchitis and bronchospastic distress.
 
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