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Pharmaceutical Grade Glibenclamide Raw Powder For Hypoglycemic Drugs Cas 10238-21-8

Pharmaceutical Grade Glibenclamide Raw Powder For Hypoglycemic Drugs Cas 10238-21-8

Pharmaceutical Grade Glibenclamide Raw Powder For Hypoglycemic Drugs Cas 10238-21-8
Pharmaceutical Grade Glibenclamide Raw Powder For Hypoglycemic Drugs Cas 10238-21-8
Pharmaceutical Grade Glibenclamide Raw Powder For Hypoglycemic Drugs Cas 10238-21-8
Product Details:
Place of Origin: China
Brand Name: LiHui
Certification: COA
Model Number: 10238-21-8
Payment & Shipping Terms:
Minimum Order Quantity: 100g
Price: Negotiated
Packaging Details: Foil Bag
Delivery Time: 3-7days after received payment
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000Kg Per Month
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Detailed Product Description
CAS: 10238-21-8 Color Or Appearance: White Crystalline Powder
Product Use: Fall Blood Sugar. It Is Suitable For Mild And Moderate Ⅱ Type Diabetes Mellitus With Unsatisfactory Therapeutic Effect Of Diet Alone. The Patients Have Certain Insulin Secretion Function Of Islet Beta Cells, And No Serious Complications Packing Specification: Aluminum Foil Bag Or Aluminum Tin 25 Kg/barrel
Execution Standard: USP42 Product Purity: 99%
The Product Level: Pharmaceutical Grade Molecular Formula: C23H28ClN3O5S
High Light:

Pharmaceutical 10238-21-8

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Glibenclamide Raw Powder

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Glibenclamide 10238-21-8

High Quality Pharmaceutical Grade Glibenclamide Raw Powder For Hypoglycemic Drugs Cas 10238-21-8

 

Product Name: Glibenclamide
CAS: 10238-21-8
MF: C23H28ClN3O5S
MW: 494
EINECS: 233-570-6
Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts; Organics; Amino Acids & Derivatis; Isotope Labeled Compounds; API's; Potassium channel; Ion Channels; Isotope Labelled Compounds; API; GLYNASE; Diabetes Research
Mol File: 10238-21-8. mol
Pharmaceutical Grade Glibenclamide Raw Powder For Hypoglycemic Drugs Cas 10238-21-8 0
Hypoglycemic Agents Glibenclamide belongs to the second generation oral sulfonylurea drugs with the mechanism of action being similar as tolbutamide and the hypoglycemic effect being strongest among sulfonylurea drugs. Its intensity of action is about 200 to 250 times of that of Tolbutamide. It can selectively act on the pancreatic β-cells, promote secretion; can enhance the hypoglycemic effect of exogeg rate of 90% to 95% and half-life of 4 to 8 hours. It is mainly consumed by the liver metabolism with six metabolites. Two of them are knownous and strengthen the post-receptor effect of . It has fast oral absorption with high protein binding rate. It begins to take effect after 30 minutes with the effect being strongest at 1.5 hours and the duration of 16 to 24 hours. It has a distribution volume of 0.1L/kg, plasma protein bindinn as hydroxylated compounds with no hypoglycemic effect and is mainly excreted from the urine and a small amount is excreted by the stool. It is clinically mainly used for the treatment of mild to moderate non- dependent diabetes mellitus.

[Pharmaceutical Grade Glibenclamide Raw Powder For Hypoglycemic Drugs Cas 10238-21-8 0]

Pharmaceutical Grade Glibenclamide Raw Powder For Hypoglycemic Drugs Cas 10238-21-8 1

Application
1. Hypoglycemic drugs, for the treatment of mild, non insulin dependent diabetes mellitus
2. Glibenclamide and glibenclamide, glibenclamide, which belongs to the second generation oral sulfonylurea drugs, with the mechanism of toluene sulfonyl Ding Niao, its hypoglycemic effect was the strongest sulfonylurea, intensity for tolbutamide 200 ~ 250 times. Be selective effect on pancreatic beta cells, promote the secretion of insulin, can enhance the hypoglycemic effect of exogenous insulin, insulin receptor after strengthening effect.
3. Glibenclamide is one of the drugs currently used to treat type 2 diabetes, the most often used, because the utility function is fast and strong, so after the application has obvious effect, can effectively control blood sugar, high blood sugar, is applicable to other sulfonylurea hypoglycemic effect not beautiful person.

[Pharmaceutical Grade Glibenclamide Raw Powder For Hypoglycemic Drugs Cas 10238-21-8 1]

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