Zhejiang Lihui Import Co.,Ltd.
Sales & Support:
 
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| Place of Origin: | India |
| Brand Name: | LiHui |
| Certification: | Hplc ISO9001 |
| Model Number: | 90717-16-1 |
| Minimum Order Quantity: | 100g |
|---|---|
| Price: | Negotiated |
| Packaging Details: | Foil Bag |
| Delivery Time: | 3-7days after received payment |
| Payment Terms: | T/T, Western Union, MoneyGram |
| Supply Ability: | 5000Kg Per Month |
| CAS: | 90717-16-1 | Color Or Appearance: | Brown Or Cream Or White Powder |
|---|---|---|---|
| Packing Specification: | Aluminum Foil Bag Or Aluminum Tin 25 Kg/barrel | Execution Standard: | USP42 |
| Product Purity: | 99% | The Product Level: | Pharmaceutical Grade |
| Molecular Formula: | C13H16ClNO·HCl |
Basic Information Edit voice
Chinese name: Hydroximide hydrochloride
Hydroxylimine Hydrochloride
Chemical name: 1- hydroxyl cyclopentyl -2- chlorophenyl -N- methylamidone hydrochloride
Chemical formula: C13H16ClNO·HCl
Molecular weight: 274.18618
Physical and chemical properties edit speech
Appearance: brown or milky white or white powder
Purity: 99%
C.A.S: 90717-16-1
Melting point: 175-185
Acid alkaline: pH 7.0-8.0
Category: Narcotic drugs pharmaceutical intermediates
Packing specification: 25kg or 20kg paper drum packing
Appearance and character
A colorless gas with a slight sweet smell
The vapor pressure
13.33 kPa (76.4 ℃)
Relative density
(water =1) 1.18;
(Air =1) 3.0
Danger tags
5 (No gas)
The main purpose
Used as refrigerant and gas - soluble insecticide launcher
Impact on the environment
First, health hazards
Route of invasion: inhalation.
Health hazard: Can cause polymer smoke fever.
Toxicological data and environmental behavior
Acute toxicity: LD501000000mg/m3, 2 hours (inhaled in rats).
Subacute and chronic toxicity: rabbits, rats and mice inhaled 0.2% concentration, 6 hours/day, a total of 10 months, no toxic reaction; 1.4% concentration, weight loss, serum protein decreased, globulin increased. Lung necropsy showed alveolar interstitial thickening, pulmonary edema, degeneration of liver, kidney and nervous system.
Mutagenicity: microbiological mutagenicity: salmonella typhimurium 33pph (24 hours), continuous. Microsomal mutagenesis: salmonella typhimurium 33pph (24 h) (continuous).
Reproductive toxicity: the lowest inhalation toxic concentration (TCL0) in rats: 50,00ppm (5 hours, 56 days for males), affecting prostate, seminal vesicle, Cowper's gland, accessory glands and urethra.
Danger: in case of high heat, the pressure in the container increases, and there is the danger of cracking and explosion.
Combustion (decomposition) products: carbon monoxide, carbon dioxide, hydrogen fluoride.
On-site emergency monitoring methods:
Instrument method
Laboratory monitoring methods:
Determination of harmful substances in air by gas chromatography (2nd Ed.), hang Shiping
Environmental standards:
The maximum allowable concentration of harmful substances in the air of the former Soviet Union workshop is 3000mg/m3
Former Soviet Union (1975) Maximum allowable concentration of harmful substances in water 10mg/L
Gefitinib Description
Gefitinib (ZD1839) (INN, , trade name Iressa, marketed by AstraZeneca and Teva), is a drug used for certain breast, lung and other cancers. Gefitinib is an EGFR inhibitor, like erlotinib, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR. However, meta-analyses have not shown any improvement in overall survival, that is, it does not extend life.
Gefitinib is used to treat non-small cell lung cancer that has spread to other parts of the body in people with certain types of tumors. Gefitinib is in a class of medications called kinase inhibitors. It works by blocking the action of a certain naturally occurring substance that may be needed to help cancer cells multiply.
How to use Gefitinib
Gefitinib comes as a tablet to take by mouth. It is usually taken with or without food once a day. Take gefitinib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take gefitinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
If you are unable to swallow the tablets, you may dissolve them in water. Place one tablet in 4 to 8 ounces (120 to 240 mL) of plain, noncarbonated drinking water. Stir with a spoon for about 15 minutes until the tablet is dissolved. Drink the mixture right away. Rinse the glass with another 4 to 8 ounces (120 to 240 mL) of water and drink the rinse water right away to be sure that you swallow all of the medication.
Your doctor may delay or permanently stop your treatment if you experience certain side effects. Be sure to tell your doctor how you are feeling during your treatment with gefitinib.
Gefitinib Specification
Tests |
Specification |
Results |
Appearance |
Slight white to white crystalline powder |
White crystalline powder |
Identification IR(1) |
Conforms to the refence |
Conforms to the refence |
Melting Point |
194.0~198.0°C |
196.0~197.0°C |
Water(KF) |
≤0.30% |
0.05% |
Assay (HPLC) |
≥99.0% |
99.9% |
Individual Purity (HPLC ) |
≤0.20% |
0.09% |
Conclusion |
Conform with company standard |
|
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Tel: +8613777515435
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